Janumet Tablet: The Ultimate Ally Against Type 2 Diabetes

1. What is Janumet Tablet?
Janumet Tablet is an oral prescription medication designed specifically for individuals managing Type 2 Diabetes. It combines two highly effective anti-diabetic agents—Sitagliptin and Metformin hydrochloride. Sitagliptin is a DPP-4 inhibitor, while Metformin is a biguanide. Together, they offer a powerful synergy to regulate blood sugar levels more effectively than either drug used alone.
Approved by the FDA and available in many countries, Janumet has been adopted as a trusted treatment for those who require more than just Metformin or lifestyle adjustments to maintain healthy glucose levels. Its role in modern diabetes care is well-established, offering not only glycemic control but also the promise of better long-term outcomes.
________________________________________
2. Composition and Ingredients
Janumet typically comes in several strengths to accommodate different patient needs:
• 50 mg Sitagliptin / 500 mg Metformin
• 50 mg Sitagliptin / 850 mg Metformin
• 50 mg Sitagliptin / 1000 mg Metformin
These dosages allow for personalized treatment plans that balance efficacy and tolerability. Each tablet contains:
• Sitagliptin Phosphate Monohydrate – helps increase the levels of incretin hormones, stimulating insulin release.
• Metformin Hydrochloride – decreases hepatic glucose production and improves insulin sensitivity.
Inactive ingredients include microcrystalline cellulose, sodium lauryl sulfate, magnesium stearate, and others, all of which support the tablet's stability and bioavailability.
________________________________________
3. How Janumet Works: Mechanism of Action
The brilliance of Janumet lies in its dual-action mechanism:
• Metformin works by reducing glucose production in the liver and improving insulin sensitivity, which helps the body use insulin more effectively.
• Sitagliptin inhibits the enzyme DPP-4, which results in increased levels of incretin hormones.