As healthcare becomes increasingly data-driven, real-world evidence (RWE) is emerging as a critical tool for assessing treatment effectiveness beyond clinical trials. By leveraging real-world data (RWD) from electronic health records, insurance claims, and wearable devices, researchers can evaluate the long-term impact, safety, and cost-effectiveness of medical interventions.
However, ensuring the reliability of RWE requires addressing key challenges such as selection bias, data integrity, and regulatory compliance. Advanced methodologies like propensity score matching (PSM), inverse probability weighting (IPW), and AI-driven analytics can help mitigate bias and enhance data quality.